Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury
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چکیده
منابع مشابه
Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury
Background: Butyrate protects against ischemic injury to the small intestine by reducing inflammation and maintaining the structure of the intestinal barrier, but is expensive, short-lived, and cannot be administered easily due to its odor. Lactate, both economical and more palatable, can be converted into butyrate by the intestinal microbiome. This study aimed to assess in a rat model whether ...
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Purpose: To evaluate the protective mechanisms afforded by pterostilbene against intestinal ischemia/reperfusion ( II/R ) injury in Wistar rats. Methods: Male Wistar rats were divided into 4 groups as follows: Control group; intestinal ischemia/reperfusion (II/R) group; pterostilbene only group (20 mg/kg) of body weight and pterostilbene followed by intestinal ischemia/reperfusion (II/R) treate...
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BACKGROUND When diseased intestine (i.e., from colon cancer, diverticulitis) requires resection, its reconnection (termed anastomosis) can be complicated by non-healing of the newly joined intestine resulting in spillage of intestinal contents into the abdominal cavity (termed anastomotic leakage). While it is suspected that the intestinal microbiota have the capacity to both accelerate and com...
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BACKGROUND Beta-adrenergic blockade has been hypothesized to have a protective effect on intestinal dysfunction and increased intestinal permeability associated with the epinephrine surge after traumatic brain injury (TBI). METHODS Wister rats were subjected to either a weight drop TBI, and intraperitoneally injected or not with labetalol, or a sham procedure (18 rats per group). After 3, 6, ...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2017
ISSN: 1664-042X
DOI: 10.3389/fphys.2017.01064